The Neuro-Immune Interface in Lymphoid Tissues
Grant number: 1161734 | Funding period: 2019 - 2021
Completed
Abstract
T cells are dynamic immune cells that protect against infections and tumours. The lymphoid tissues also contain networks of nerves that can control immune responses. Our work has revealed neural circuits that regulate T cell behaviour and changes to the lymphoid tissue nervous system due to infection. This project will use advanced microscopy and innovative tools to determine the neuro-immune interface in lymphoid tissues and reveal new targets to modulate immune responses.